1) Despite facing numerous setbacks, she refused to give up on her dream of becoming a doctor.

2) If you keep trying, you will succeed - never give up.

3) He was tempted to give up during the marathon, but the crowd's cheers motivated him to keep going.

4) It's important to never give up on yourself, even when things get tough.

5) The rescue team did not give up until they found the missing hiker.

6) Rather than give up after failing the test, she decided to study harder for the next one.

7) When life gets difficult, remember to keep pushing forward and never give up.

8) Some people give up too easily when faced with challenges, missing out on opportunities for growth.

9) Despite the odds being against them, the team refused to give up and pulled off an amazing victory.

10) Giving up is not an option for those who are determined to reach their goals.

11) Sure, here are some example sentences using the word 'Give Up':

12) She refused to give up on her dreams, no matter how challenging things got.

13) Despite facing numerous obstacles, he never once considered giving up.

14) The team showed great resilience and determination, never willing to give up until they reached their goal.